Scaffold Of Heart Tissue From Tasar Silk Worm

Scientists are nearing the process of replacing the damaged heart muscle tissue with that of a material made from tasar silk worm. The experiment is successful in mice but a little more research is needed in the human arena.

It is not possible to regenerate the human heart muscle and a scar tissue takes the place of damaged muscle cells. Scientists have found a replacement tissue which can be grown in the laboratory setting. The best thing is that the replacement tissue is produced from silk made by tasar worms.

Researchers from the Max Plank Institute of Heart and Lung research have produced coin sized discs from the cocoon of the tasar silk worm. They have loaded the cardiac muscle cells on to the three dimensional scaffold which was created from silk. To be clearer a scaffold is a network of proteins that hold together and supports a variety of living tissues.

 The fiber produced by these worms has proteins on its surface which easily ease the sticking of heart muscle cells. The silk fibers are coarser and the muscle cells thrive and forms a three dimensional tissue structure.

To test it on humans the researchers have to use human stem cells to avoid any immune reaction. But the conversion of stem cells to heart muscle cells need more research.

Take care,
Swarnam